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Cellosaurus RW-2982 (CVCL_D174)

[Text version]
Cell line name RW-2982
Synonyms RW2982
Accession CVCL_D174
Resource Identification Initiative To cite this cell line use: RW-2982 (RRID:CVCL_D174)
Comments Population: Caucasian.
Doubling time: 58.41 hours (PubMed=25944804).
Microsatellite instability: Stable (MSS) (PubMed=24755471).
Omics: Transcriptomics; RNAseq.
Derived from site: Metastatic; Omentum; UBERON=UBERON_0003688.
Sequence variations
Disease Colon mucinous adenocarcinoma (NCIt: C7966)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C3I3 (RW-2982-NS)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
Publications

CLPUB00125
Lance M. Tibbetts, Ming Y. Chu, Ellen N. Spremulli, Elizabeth Hortense Leduc, Paul Calabresi;
Loss and restoration of tumorigenicity in a human mesothelioma cell line.
Proc. Am. Assoc. Cancer Res. 25:45.176-45.176(1984)

PubMed=2837323
Lance M. Tibbetts, Ming Y. Chu, Michael P. Vezeridis, Paula G. Miller, Linda L. Tibbetts, Marian H. Poisson, Paul D. Camara, Paul Calabresi;
Cell culture of the mucinous variant of human colorectal carcinoma.
Cancer Res. 48:3751-3759(1988)

PubMed=8422623; DOI=10.1002/1097-0142(19930115)71:2<315::AID-CNCR2820710208>3.0.CO;2-B
Lance M. Tibbetts, Craig M. Doremus, George N. Tzanakakis, Michael P. Vezeridis;
Liver metastases with 10 human colon carcinoma cell lines in nude mice and association with carcinoembryonic antigen production.
Cancer 71:315-321(1993)

PubMed=20570890; DOI=10.1158/0008-5472.CAN-10-0192; PMCID=PMC2943514
Manickam Janakiraman, Efsevia Vakiani, Zhao-Shi Zeng, Christine A. Pratilas, Barry Stephen Taylor, Dhananjay Chitale, Ensar Halilovic, Manda Wilson, Kety Huberman, Julio Cezar Marques Ricarte Filho, Yogindra Persaud ...Show all 21 authors... , Douglas A. Levine, James Alexander Fagin, Suresh C. Jhanwar, John M. Mariadason, Alex Lash, Marc Ladanyi, Leonard B. Saltz, Adriana Heguy, Philip B. Paty, David B. Solit; Show fewer authors
Genomic and biological characterization of exon 4 KRAS mutations in human cancer.
Cancer Res. 70:5901-5911(2010)

PubMed=24755471; DOI=10.1158/0008-5472.CAN-14-0013
Dmitri Mouradov, Clare Sloggett, Robert N. Jorissen, Christopher G. Love, Shan Li, Antony Wilks Burgess, Diego Arango, Robert L. Strausberg, Daniel Buchanan, Samuel Wormald, Liam O'Connor ...Show all 17 authors... , Jennifer L. Wilding, David C. Bicknell, Ian Philip Mark Tomlinson, Walter Fred Bodmer, John M. Mariadason, Oliver M. Sieber; Show fewer authors
Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
Cancer Res. 74:3238-3247(2014)

PubMed=25944804; DOI=10.1158/1078-0432.CCR-14-2457
Sarah Bazzocco, Higinio Dopeso, Fernando Carton-Garcia, Irati Macaya, Elena Andretta, Fiona Chionh, Paulo Rodrigues, Miriam Garrido, Hafid Alazzouzi, Rocio Nieto, Alex Sanchez ...Show all 15 authors... , Simo Schwartz Jr., Josipa Bilic, John M. Mariadason, Diego Arango; Show fewer authors
Highly expressed genes in rapidly proliferating tumor cells as new targets for colorectal cancer treatment.
Clin. Cancer Res. 21:3695-3704(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_D174
ColonAtlas; RW2982
Encyclopedic resources Wikidata; Q54951483
Gene expression databases GEO; GSM1346885
Polymorphism and mutation databases Cosmic; 1479600
Cosmic; 1676748
Cosmic; 1803949
Cosmic; 2302004
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number20