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Cellosaurus K562-Lucena 1 (CVCL_D162)

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Cell line name K562-Lucena 1
Synonyms K562-Lucena; K562-LUCENA; Lucena 1; Lucena
Accession CVCL_D162
Resource Identification Initiative To cite this cell line use: K562-Lucena 1 (RRID:CVCL_D162)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_28445; Vincristine (VCR).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=11246270; DOI=10.1590/S0001-37652001000100007
Vivian Mary Rumjanek, Gilma Santos Trindade, Karen Wagner-Souza, Michele C. Meletti-de-Oliveira, Luis F. Marques-Santos, Raquel C. Maia, Marcia Alves Marques Capella;
Multidrug resistance in tumour cells: characterization of the multidrug resistant cell line K562-Lucena 1.
An. Acad. Bras. Cienc. 73:57-69(2001)

Cross-references
Cell line collections (Providers) BCRJ; 0127
Chemistry resources ChEMBL-Cells; CHEMBL4630604
ChEMBL-Targets; CHEMBL4630704
PubChem_Cell_line; CVCL_D162
Encyclopedic resources Wikidata; Q54899396
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number24