| Cell line name |
YBLi006-A |
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| Synonyms |
YBL/PH/2022/0025 |
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| Accession |
CVCL_D0QA |
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| Resource Identification Initiative |
To cite this cell line use: YBLi006-A (RRID:CVCL_D0QA) |
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| Comments |
From: Yashraj Biotechnology Ltd; Navi Mumbai; India.
Population: Indian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. |
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| Sequence variations |
- Mutation; HGNC; 1100; BRCA1; Simple; p.Pro871Leu (c.2612C>T); ClinVar=VCV000041812; Zygosity=Heterozygous (PubMed=37290137).
- Mutation; HGNC; 1100; BRCA1; Simple; p.Glu1038Gly (c.3113A>G); ClinVar=VCV000041815; Zygosity=Heterozygous (PubMed=37290137).
- Mutation; HGNC; 1100; BRCA1; Simple; p.Lys1183Arg (c.3548A>G); dbSNP=rs16942; Zygosity=Heterozygous (PubMed=37290137).
- Mutation; HGNC; 1100; BRCA1; Simple; p.Ser1613Gly (c.4837A>G); ClinVar=VCV000041827; Zygosity=Heterozygous (PubMed=37290137).
- Mutation; HGNC; 25568; FANCI; Simple; p.Gly27Val (c.80G>T); Zygosity=Heterozygous (PubMed=37290137).
- Mutation; HGNC; 25568; FANCI; Simple; p.Ala86Val (c.257C>T); ClinVar=VCV000257484; Zygosity=Heterozygous (PubMed=37290137).
- Mutation; HGNC; 25568; FANCI; Simple; p.Cys742Ser (c.2225G>C); ClinVar=VCV000257482; Zygosity=Heterozygous (PubMed=37290137).
|
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| Disease |
BRCA1-associated hereditary breast and ovarian cancer syndrome (NCIt: C36100)
Hereditary breast cancer (ORDO: Orphanet_227535) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Female |
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| Age at sampling |
49Y |
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| Category |
Induced pluripotent stem cell |
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| Publications | PubMed=37290137; DOI=10.1016/j.scr.2023.103128
Chitrangi S., Vaity P., Jamdar A., Sarkar J., Bhatt S.
Derivation of breast cancer patient derived human induced pluripotent stem cell line (YBLi006-A) with FANC-BRCA gene mutations: a resource for precision & personalized medicine.
Stem Cell Res. 70:103128-103128(2023) |
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| Cross-references |
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| Cell line databases/resources |
hPSCreg; YBLi006-A
|
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| Biological sample resources |
BioSamples; SAMEA112910788
|
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| Encyclopedic resources |
Wikidata; Q123033952
|
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| Entry history |
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| Entry creation | 05-Oct-2023 |
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| Last entry update | 30-Jan-2024 |
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| Version number | 2 |
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