Cellosaurus cell line XWHNi002-A (CVCL

Cross-references
Cell line name	XWHNi002-A
Accession	CVCL_D0Q2
Resource Identification Initiative	To cite this cell line use: XWHNi002-A (RRID:CVCL_D0Q2)
Comments	From: Department of Neurology, Xuan Wu Hospital; Beijing; China. Population: Chinese. Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations	Mutation; HGNC; HGNC:620; APP; Simple; p.Val717Ile (c.2149G>A); ClinVar=VCV000018088; Zygosity=Heterozygous (PubMed=37356183).
Disease	Alzheimer's disease 1 (NCIt: C146894) Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	35Y
Category	Induced pluripotent stem cell
Publications	PubMed=37356183; DOI=10.1016/j.scr.2023.103149 Wen-Xian Sun, Pin Wang, Jin Gong, Yu-Fei Chen, Yu-Ting Yang, He-Ya Luan, Shao-Qi Li, Rui-Na Li, Cui-Bai Wei; Generation of induced pluripotent stem cell line (XWHNi002-A) from a female with APP gene mutation. Stem Cell Res. 71:103149-103149(2023)
Cell line databases/resources	hPSCreg; XWHNi002-A
Biological sample resources	BioSamples; SAMEA112859424
Encyclopedic resources	Wikidata; Q123033943
Entry history
Entry creation	05-Oct-2023
Last entry update	10-Apr-2025
Version number	4