Cellosaurus cell line UPITTi004-A (CVCL

Cellosaurus UPITTi004-A (CVCL_D0P6)

[Text version]

Cell line name

UPITTi004-A

Synonyms

CN090 C5A5J2

Accession

CVCL_D0P6

Resource Identification Initiative

To cite this cell line use: UPITTi004-A (RRID:CVCL_D0P6)

Comments

From: University of Pittsburgh; Pittsburgh; USA.
Population: African American.
Derived from site: In situ; Testis; UBERON=UBERON_0000473.
Cell type: Fibroblast; CL=CL_0000057.

Sequence variations

Mutation; HGNC; HGNC:4827; HBB; Simple; p.Glu7Val (c.20A>T) (E6V); ClinVar=VCV000015333; Zygosity=Homozygous (PubMed=38000347).

Disease

Sickle cell disease (NCIt: C34383)
Sickle cell anemia (ORDO: Orphanet_232)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_D0P7 ! UPITTi004-B

Sex of cell

Male

Age at sampling

12Y

Category

Induced pluripotent stem cell

STR profile

Source(s): PubMed=38000347

Markers:

Amelogenin	X,Y
CSF1PO	10
D3S1358	15
D5S818	12
D7S820	9,12
D8S1179	13,17
D13S317	12,13
D16S539	11,13
D18S51	16,19
D21S11	28,29
FGA	26,28
Penta D	5,11
Penta E	5,7
TH01	8,9
TPOX	8,9
vWA	16

Publications

PubMed=38000347; DOI=10.1016/j.scr.2023.103257; PMCID=PMC10845156
Mitchell R. Harancher, Meena Sukhwani, Carlos A. Castro, Michael Harrison Hsieh, Kyle E. Orwig;
Generation of two isogenic sickle cell disease induced pluripotent stem cell lines from testicular fibroblasts.
Stem Cell Res. 73:103257-103257(2023)

Cross-references

Cell line databases/resources

hPSCreg; UPITTi004-A

Biological sample resources

BioSamples; SAMEA114066390

Encyclopedic resources

Wikidata; Q123033755

Entry history

Entry creation

05-Oct-2023

Last entry update

19-Dec-2024

Version number