Cellosaurus cell line LCSBi013-A (CVCL

Cellosaurus LCSBi013-A (CVCL_D0HL)

Cross-references
Cell line name	LCSBi013-A
Synonyms	GL2; iPSC F0245 CL1_1
Accession	CVCL_D0HL
Resource Identification Initiative	To cite this cell line use: LCSBi013-A (RRID:CVCL_D0HL)
Comments	From: Luxembourg Centre for Systems Biomedicine; Belvaux; Luxembourg. Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:4177; GBA1; Simple; p.Asn409Ser (c.1226A>G) (N370S); ClinVar=VCV000004290; Zygosity=Heterozygous (PubMed=37832355). Mutation; HGNC; HGNC:18618; LRRK2; Simple; p.Gly2019Ser (c.6055G>A); ClinVar=VCV000001940; Zygosity=Heterozygous (PubMed=37832355).
Disease	Parkinson disease 8, autosomal dominant (NCIt: C198605) Hereditary late-onset Parkinson disease (ORDO: Orphanet_411602)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	67Y
Category	Induced pluripotent stem cell
Publications	PubMed=37832355; DOI=10.1016/j.scr.2023.103212 Christiane Oleksy, Francois Massart, Stefano Goldwurm, Alessia Arado, Giuseppe Arena, Ibrahim Boussaad, Rejko Kruger; Generation and characterization of induced pluripotent stem cells from a Parkinson's disease patient carrying the digenic LRRK2 p.G2019S and GBA1 p.N409S mutations. Stem Cell Res. 72:103212-103212(2023)
Cell line databases/resources	hPSCreg; LCSBi013-A
Biological sample resources	BioSamples; SAMEA113634167
Encyclopedic resources	Wikidata; Q123032942
Entry history
Entry creation	05-Oct-2023
Last entry update	19-Dec-2024
Version number	3