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Cellosaurus HES-2 (CVCL_D093)

[Text version]
Cell line name HES-2
Synonyms hES-2; HES 2; HES2; hES2; ES02; ESIBIOe002-A; ESIBIe002-A
Accession CVCL_D093
Resource Identification Initiative To cite this cell line use: HES-2 (RRID:CVCL_D093)
Comments From: ESI BIO - BioTime, Inc. (ES Cell International); Alameda; USA.
From: Monash University; Melbourne; Australia.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC03-02.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
HLA typing Source: PubMed=16919167
Class I
HLA-AA*02:03,02
HLA-BB*46,48
HLA-CC*01,08
Class II
HLA-DQDQB1*04,06
HLA-DRDRB1*04,15
DRB5*01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_QX78 (ESIBIe002-A-1)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): PubMed=16919167; WiCell=es02

Markers:
AmelogeninX
CSF1PO11
D5S81811
D7S8209,11
D13S3178,11
D16S5399,12
TH017,9
TPOX8,12
vWA18,20

Run an STR similarity search on this cell line
Web pages Info; StemCellDB; -; https://stemcelldb.nih.gov/cellLineDetails/affy/30
Info; StemCellDB; -; https://stemcelldb.nih.gov/cellLineDetails/Agilent/30
Publications

PubMed=10748519; DOI=10.1038/74447
Benjamin E. Reubinoff, Martin F. Pera, Chui-Yee Fong, Alan Osborne Trounson, Ariff Bongso;
Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro.
Nat. Biotechnol. 18:399-404(2000)

PubMed=16919167; DOI=10.1186/1741-7007-4-28; PMCID=PMC1601965
Richard Josephson, Gregory R. Sykes, Ying Liu, Carol J. Ording, Wei-Ning Xu, Xian-Min Zeng, Soojung Shin, Jeanne Frances Loring, Anirban Maitra, Mahendra Surendra Rao, Jonathan M. Auerbach;
A molecular scheme for improved characterization of human embryonic stem cell lines.
BMC Biol. 4:28.1-28.13(2006)

PubMed=17572666; DOI=10.1038/nbt1318
Oluseun Adewumi, Behrouz Aflatoonian, Lars Ahrlund-Richter, Michal Amit, Peter W. Andrews, Gemma Beighton, Paul A. Bello, Nissim Benvenisty, Lorraine S. Berry, Simon Bevan, Barak Blum ...Show all 85 authors... , Justin Brooking, Kevin G. Chen, Andre B.-H. Choo, Gary A. Churchill, Marie Corbel, Ivan Damjanov, Jonathan S. Draper, Petr Dvorak, Katarina Emanuelsson, Roland A. Fleck, Angela Ford, Karin Gertow, Marina Gertsenstein, Paul J. Gokhale, Rebecca S. Hamilton, Ales Hampl, Lyn E. Healy, Outi Hovatta, Johan Hyllner, Marta P. Imreh, Joseph Itskovitz-Eldor, Jamie Jackson, Jacqueline L. Johnson, Mark Jones, Kehkooi Kee, Benjamin L. King, Barbara B. Knowles, Majlinda Lako, Franck Lebrin, Barbara S. Mallon, Daisy Manning, Yoav Mayshar, Ronald Davies Graham McKay, Anna E. Michalska, Milla Mikkola, Maria Mileikovsky, Stephen Lewis Minger, Harry D. Moore, Christine L. Mummery, Andras Nagy, Norio Nakatsuji, Carmel M. O'Brien, Steve Kah-Weng Oh, Cia Olsson, Timo Otonkoski, Kye-Yoon Park, Robert Passier, Hema Patel, Minal J. Patel, Roger Arnold Pedersen, Martin F. Pera, Marian S. Piekarczyk, Renee A. Reijo Pera, Benjamin E. Reubinoff, Allan J. Robins, Janet Rossant, Peter Rugg-Gunn, Thomas C. Schulz, Henrik Semb, Eric S. Sherrer, Henrike Siemen, Glyn N. Stacey, Miodrag Stojkovic, Hirofumi Suemori, Jin Szatkiewicz, Tikva Tako Turetsky, Timo Tuuri, Stieneke van den Brink, Kristina Vintersten, Sanna Vuoristo, Dorien Ward-van Oostwaard, Thomas A. Weaver, Lesley A. Young, Wei-Dong Zhang; Show fewer authors
International Stem Cell Initiative
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=18772870; DOI=10.1038/nprot.2008.140
Stefan R. Braam, Chris Denning, Elena Matsa, Lorraine E. Young, Robert Passier, Christine L. Mummery;
Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification.
Nat. Protoc. 3:1435-1443(2008)

PubMed=23117585; DOI=10.1016/j.scr.2012.09.002; PMCID=PMC3590800
Barbara S. Mallon, Joshua G. Chenoweth, Kory R. Johnson, Rebecca S. Hamilton, Paul J. Tesar, Amarendra S. Yavatkar, Leonard J. Tyson, Kyeyoon Park, Kevin G. Chen, Yang-Cheng Fann, Ronald Davies Graham McKay;
StemCellDB: the human pluripotent stem cell database at the National Institutes of Health.
Stem Cell Res. 10:57-66(2013)

Cross-references
Cell line collections (Providers) WiCell; es02
Cell line databases/resources hPSCreg; ESIBIe002-A
SKIP; SKIP001942
Biological sample resources BioSample; SAMN03471889
Encyclopedic resources Wikidata; Q54882906
Experimental variables resources EFO; EFO_0003048
Gene expression databases GEO; GSM856723
GEO; GSM862740
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number21