Cellosaurus cell line HES-2 (CVCL

Cellosaurus HES-2 (CVCL_D093)

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Cell line name

HES-2

Synonyms

hES-2; HES 2; HES2; hES2; ES02; ESIBIOe002-A; ESIBIe002-A

Accession

CVCL_D093

Resource Identification Initiative

To cite this cell line use: HES-2 (RRID:CVCL_D093)

Comments

From: ESI BIO - BioTime, Inc. (ES Cell International); Alameda; USA.
From: Monash University; Melbourne; Australia.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC03-02.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.

HLA typing

Source: PubMed=16919167

Class I
HLA-A	A*02:03,02
HLA-B	B*46,48
HLA-C	C*01,08
Class II
HLA-DQ	DQB1*04,06
HLA-DR	DRB1*04,15
	DRB5*01

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_QX78 (ESIBIe002-A-1)

Sex of cell

Female

Age at sampling

Blastocyst stage

Category

Embryonic stem cell

STR profile

Source(s): PubMed=16919167; WiCell=es02

Markers:

Amelogenin	X
CSF1PO	11
D5S818	11
D7S820	9,11
D13S317	8,11
D16S539	9,12
TH01	7,9
TPOX	8,12
vWA	18,20

Web pages

Info; StemCellDB; -; https://stemcelldb.nih.gov/cellLineDetails/affy/30
Info; StemCellDB; -; https://stemcelldb.nih.gov/cellLineDetails/Agilent/30

Publications

PubMed=10748519; DOI=10.1038/74447
Benjamin E. Reubinoff, Martin F. Pera, Chui-Yee Fong, Alan Osborne Trounson, Ariff Bongso;
Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro.
Nat. Biotechnol. 18:399-404(2000)

PubMed=16919167; DOI=10.1186/1741-7007-4-28; PMCID=PMC1601965
Richard Josephson, Gregory R. Sykes, Ying Liu, Carol J. Ording, Wei-Ning Xu, Xian-Min Zeng, Soojung Shin, Jeanne Frances Loring, Anirban Maitra, Mahendra Surendra Rao, Jonathan M. Auerbach;
A molecular scheme for improved characterization of human embryonic stem cell lines.
BMC Biol. 4:28.1-28.13(2006)

PubMed=17572666; DOI=10.1038/nbt1318
Oluseun Adewumi, Behrouz Aflatoonian, Lars Ahrlund-Richter, Michal Amit, Peter W. Andrews, Gemma Beighton, Paul A. Bello, Nissim Benvenisty, Lorraine S. Berry, Simon Bevan, Barak Blum ...Show all 85 authors... , Justin Brooking, Kevin Gang Chen, Andre B.-H. Choo, Gary Allen Churchill, Marie Corbel, Ivan Damjanov, Jonathan S. Draper, Petr Dvorak, Katarina Emanuelsson, Roland A. Fleck, Angela Ford, Karin Gertow, Marina Gertsenstein, Paul J. Gokhale, Rebecca S. Hamilton, Ales Hampl, Lyn E. Healy, Outi Hovatta, Johan Hyllner, Marta P. Imreh, Joseph Itskovitz-Eldor, Jamie Jackson, Jacqueline L. Johnson, Mark Jones, Kehkooi Kee, Benjamin L. King, Barbara B. Knowles, Majlinda Lako, Franck Lebrin, Barbara S. Mallon, Daisy Manning, Yoav Mayshar, Ronald Davies Graham McKay, Anna E. Michalska, Milla Mikkola, Maria Mileikovsky, Stephen Lewis Minger, Harry D. Moore, Christine Lindsay Mummery, Andras Nagy, Norio Nakatsuji, Carmel M. O'Brien, Steve Kah-Weng Oh, Cia Olsson, Timo Otonkoski, Kye-Yoon Park, Robert Passier, Hema Patel, Minal J. Patel, Roger Arnold Pedersen, Martin F. Pera, Marian S. Piekarczyk, Renee A. Reijo Pera, Benjamin E. Reubinoff, Allan J. Robins, Janet Rossant, Peter Rugg-Gunn, Thomas C. Schulz, Henrik Semb, Eric S. Sherrer, Henrike Siemen, Glyn N. Stacey, Miodrag Stojkovic, Hirofumi Suemori, Jin Szatkiewicz, Tikva Tako Turetsky, Timo Tuuri, Stieneke van den Brink, Kristina Vintersten, Sanna Vuoristo, Dorien Ward-van Oostwaard, Thomas A. Weaver, Lesley A. Young, Wei-Dong Zhang; Show fewer authors
International Stem Cell Initiative
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=18772870; DOI=10.1038/nprot.2008.140
Stefan R. Braam, Chris Denning, Elena Matsa, Lorraine E. Young, Robert Passier, Christine Lindsay Mummery;
Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification.
Nat. Protoc. 3:1435-1443(2008)

PubMed=23117585; DOI=10.1016/j.scr.2012.09.002; PMCID=PMC3590800
Barbara S. Mallon, Joshua G. Chenoweth, Kory R. Johnson, Rebecca S. Hamilton, Paul J. Tesar, Amarendra S. Yavatkar, Leonard J. Tyson, Kyeyoon Park, Kevin Gang Chen, Yang-Cheng Fann, Ronald Davies Graham McKay;
StemCellDB: the human pluripotent stem cell database at the National Institutes of Health.
Stem Cell Res. 10:57-66(2013)

Cross-references

Cell line collections (Providers)

WiCell; es02

Cell line databases/resources

hPSCreg; ESIBIe002-A
SKIP; SKIP001942

Biological sample resources

BioSample; SAMN03471889

Encyclopedic resources

Wikidata; Q54882906

Experimental variables resources

EFO; EFO_0003048

Gene expression databases