Cellosaurus cell line M88 (CVCL

Cellosaurus M88 (CVCL_D035)

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Cell line name

M88

Synonyms

EST135

Accession

CVCL_D035

Resource Identification Initiative

To cite this cell line use: M88 (RRID:CVCL_D035)

Comments

Omics: Variations; Array-based CGH.

Sequence variations

Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17260012; PubMed=23851445).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys176Tyr (c.527G>A); ClinVar=VCV000186451; Zygosity=Unspecified (PubMed=17260012; PubMed=23851445).

Disease

Cutaneous melanoma (NCIt: C3510)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

Age unspecified

Category

Cancer cell line

STR profile

Source(s): ESTDAB=ESTDAB-135

Markers:

Amelogenin	X,Y
CSF1PO	9,11
D3S1358	18
D5S818	11
D7S820	12
D13S317	11
FGA	25
TH01	6
TPOX	10
vWA	16

Publications

PubMed=17260012; DOI=10.1038/sj.onc.1210252
Goran Jonsson, Christina Dahl, Johan Staaf, Troy Sandberg, Par-Ola Bendahl, Markus Ringner, Per Guldberg, Ake Borg;
Genomic profiling of malignant melanoma using tiling-resolution arrayCGH.
Oncogene 26:4738-4748(2007)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Christina Dahl, Claus Christensen, Goran Jonsson, Anders Lorentzen, Mette Louise Skjodt, Ake Borg, Graham Pawelec, Per Guldberg;
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_D035
ESTDAB; ESTDAB-135

Encyclopedic resources

Wikidata; Q54903651

Gene expression databases

GEO; GSM156018

Polymorphism and mutation databases

Cosmic; 1047645
Cosmic; 2163833
IARC_TP53; 26072
Progenetix; CVCL_D035

Entry history

Entry creation

22-Oct-2012

Last entry update

14-Aug-2025

Version number