Cellosaurus cell line T1889 (CVCL

Cellosaurus T1889 (CVCL_D024)

Cross-references
Cell line name	T1889
Synonyms	TC1889; T-1889; 1889c
Accession	CVCL_D024
Resource Identification Initiative	To cite this cell line use: T1889 (RRID:CVCL_D024)
Comments	Omics: Variations; Array-based CGH.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Ile (c.738G>T); ClinVar=VCV000968639; Zygosity=Homozygous (PubMed=34781947).
Disease	Thymic undifferentiated carcinoma (NCIt: C35718) Thymic carcinoma (ORDO: Orphanet_99868)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	56Y
Category	Cancer cell line
Publications	PubMed=18360827; DOI=10.1002/ijc.23335 Ehemann V., Kern M.A., Breinig M., Schnabel P.A., Gunawan B., Schulten H.-J., Schlaeger C., Radlwimmer B., Steger C.M., Dienemann H., Lichter P., Schirmacher P., Rieker R.J. Establishment, characterization and drug sensitivity testing in primary cultures of human thymoma and thymic carcinoma. Int. J. Cancer 122:2719-2725(2008) PubMed=34781947; DOI=10.1186/s12916-021-02158-3; PMCID=PMC8594228 Muller D., Mazzeo P., Koch R., Bosherz M.-S., Welter S., von Hammerstein-Equord A.F., Hinterthaner M., Cordes L., Belharazem D., Marx A., Strobel P., Kuffer S. Functional apoptosis profiling identifies MCL-1 and BCL-xL as prognostic markers and therapeutic targets in advanced thymomas and thymic carcinomas. BMC Med. 19:300.1-300.14(2021)
Encyclopedic resources	Wikidata; Q54971425
Gene expression databases	GEO; GSM577204
Polymorphism and mutation databases	Cosmic; 1498256
Entry history
Entry creation	22-Oct-2012
Last entry update	10-Apr-2025
Version number	10