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Cellosaurus INEUi002-A-2 (CVCL_C9LH)

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Cell line name INEUi002-A-2
Synonyms PKP2 KO
Accession CVCL_C9LH
Resource Identification Initiative To cite this cell line use: INEUi002-A-2 (RRID:CVCL_C9LH)
Comments From: Instituto de Neurociencias; Buenos Aires; Argentina.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:9024; PKP2.
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Disease Familial arrhythmogenic right ventricular dysplasia 9 (NCIt: C173471)
Familial isolated arrhythmogenic ventricular dysplasia, right dominant form (ORDO: Orphanet_293910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_DQ93 (INEUi002-A)
Sex of cell Male
Age at sampling Age unspecified
Category Induced pluripotent stem cell
Publications

PubMed=37393721; DOI=10.1016/j.scr.2023.103157
Guadalupe Amin, Sheila Lucia Castaneda, Federico Zabalegui, Carolina Belli, Catalina Atorrasagasti, Santiago Gabriel Miriuka, Lucia Natalia Moro;
Generation of two edited iPSCs lines by CRISPR/Cas9 with point mutations in PKP2 gene for arrhythmogenic cardiomyopathy in vitro modeling.
Stem Cell Res. 71:103157-103157(2023)

Cross-references
Cell line databases/resources hPSCreg; INEUi002-A-2
Encyclopedic resources Wikidata; Q123032703
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number3