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Cellosaurus IMSUTi002-A-2 (CVCL_C9HE)

[Text version]
Cell line name IMSUTi002-A-2
Synonyms 7F3955-KMT2A-AFF1; CRIEPIi003-A-2
Accession CVCL_C9HE
Resource Identification Initiative To cite this cell line use: IMSUTi002-A-2 (RRID:CVCL_C9HE)
Comments From: Sustainable System Research Laboratory, Central Research Institute of Electric Power Industry (CRIEPI); Chiba; Japan.
Population: Japanese.
Characteristics: Transfected with a Tet-on system so as to induce the expression of EGFP and the KMT2A-AFF1 fusion protein with the addition of doxycycline to the culture medium (PubMed=37639801).
Transfected with: HGNC; 7135; AFF1 (KMT2-AFF1/MLL-AF4 fusion).
Transfected with: HGNC; 7132; KMT2A (KMT2-AFF1/MLL-AF4 fusion).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; P04483; Escherichia coli Tn10 tetR.
Transfected with: UniProtKB; P06492; Human herpesvirus 1 VP16 (UL28) (with p.Met1_Arg360del).
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_XI76 (IMSUTi002-A)
Sex of cell Male
Age at sampling Age unspecified
Category Induced pluripotent stem cell

PubMed=37639801; DOI=10.1016/j.scr.2023.103185
Takahashi M.
Generation of a human induced pluripotent stem cell line harboring the infant leukemia-associated fusion gene, KMT2A-AFF1 (IMSUTi002-A-2).
Stem Cell Res. 71:103185-103185(2023)

Cell line databases/resources hPSCreg; IMSUTi002-A-2
Encyclopedic resources Wikidata; Q123032699
Entry history
Entry creation05-Oct-2023
Last entry update30-Jan-2024
Version number2