Cellosaurus logo
expasy logo

Cellosaurus 6C1.10 (CVCL_C9FT)

[Text][XML][JSON]
Cell line name 6C1.10
Accession CVCL_C9FT
Resource Identification Initiative To cite this cell line use: 6C1.10 (RRID:CVCL_C9FT)
Comments Doubling time: 17 hours (PubMed=9631008).
Monoclonal antibody isotype: IgG1, kappa.
Monoclonal antibody target: UniProtKB; P01730; Human CD4.
Miscellaneous: As the immunized splenic B-cells are from humanized transgenic HC2/KCo5/JHD/JCkappaD mice the produced mAB is of human origin.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_4032 (P3X63Ag8.653)
Category Hybridoma
Publications

PubMed=9631008; DOI=10.1038/nbt0796-845
Dianne M. Fishwild, Susan L. O'Donnell, Tasha Bengoechea, Debra V. Hudson, Fiona Harding, Susan L. Bernhard, Debbie Jones, Robert M. Kay, Kay M. Higgins, Stephen R. Schramm, Nils Lonberg;
High-avidity human IgG kappa monoclonal antibodies from a novel strain of minilocus transgenic mice.
Nat. Biotechnol. 14:845-851(1996)

Patent=US8231877
Nils Lonberg, Robert M. Kay, Dianne M. Fishwild;
Heterologous antibodies which bind human CD4.
Patent number US8231877, 31-Jul-2012

Cross-references
Encyclopedic resources Wikidata; Q123030314
Entry history
Entry creation05-Oct-2023
Last entry update30-Jan-2024
Version number2