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Cellosaurus Panc 10.05/Cas9-hyg (CVCL_C9DS)

[Text version]
Cell line name Panc 10.05/Cas9-hyg
Accession CVCL_C9DS
Resource Identification Initiative To cite this cell line use: Panc 10.05/Cas9-hyg (RRID:CVCL_C9DS)
Comments Population: Caucasian.
Characteristics: Stably expresses a EF1a-Cas9-HA-SV40-EGFP-IRES-HygR construct (GeneCopoeia=SL570).
Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ile255Asn (c.764T>A); ClinVar=VCV000232289; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1639 (Panc 10.05)
Sex of cell Male
Age at sampling 81Y
Category Cancer cell line
Cell line collections (Providers) GeneCopoeia; SL570
Encyclopedic resources Wikidata; Q123033255
Entry history
Entry creation05-Oct-2023
Last entry update30-Jan-2024
Version number2