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Cellosaurus SNU-16/Cas9-hyg (CVCL_C9DM)

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Cell line name SNU-16/Cas9-hyg
Accession CVCL_C9DM
Resource Identification Initiative To cite this cell line use: SNU-16/Cas9-hyg (RRID:CVCL_C9DM)
Comments Population: Korean.
Characteristics: Stably expresses a EF1a-Cas9-HA-SV40-EGFP-IRES-HygR construct (GeneCopoeia=SL545).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene fusion; HGNC; HGNC:1681; CD44 + HGNC; HGNC:10940; SLC1A2; Name(s)=CD44-SLC1A2 (from parent cell line).
  • Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Lys1358fs*2 (c.4065_4066insTTGA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:667; RHOA; Simple; p.Arg5Trp (c.13C>T); ClinVar=VCV003765045; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:667; RHOA; Simple; p.Phe39Leu (c.117T>G); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr205Phe (c.614A>T); ClinVar=VCV000376682; Zygosity=Homozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0076 (SNU-16)
Sex of cell Female
Age at sampling 33Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) GeneCopoeia; SL545
Encyclopedic resources Wikidata; Q123033539
Entry history
Entry creation05-Oct-2023
Last entry update14-Aug-2025
Version number6