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Cellosaurus CAMA-1/Cas9-hyg (CVCL_C9DC)

[Text version]
Cell line name CAMA-1/Cas9-hyg
Accession CVCL_C9DC
Resource Identification Initiative To cite this cell line use: CAMA-1/Cas9-hyg (RRID:CVCL_C9DC)
Comments Population: Caucasian.
Characteristics: Stably expresses a EF1a-Cas9-HA-SV40-EGFP-IRES-HygR construct (GeneCopoeia=SL562).
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:1748; CDH1; Simple; c.1712-1G>A; Zygosity=Homozygous; Note=Splice acceptor mutation (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Asp92His (c.274G>C); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Thr (c.839G>C); ClinVar=VCV000012368; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1115 (CAMA-1)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) GeneCopoeia; SL562
Encyclopedic resources Wikidata; Q123030852
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number4