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Cellosaurus A549/Cas9 AAVS1 (CVCL_C9BK)

[Text version]
Cell line name A549/Cas9 AAVS1
Accession CVCL_C9BK
Resource Identification Initiative To cite this cell line use: A549/Cas9 AAVS1 (RRID:CVCL_C9BK)
Comments Population: Caucasian.
Characteristics: Stably expresses a CBh-3xFLAG-Cas9-NLS-bGHPolyA-EF1a-copGFP-T2A-PuroR-SV40pa construct from the AAVS1 safe locus (GeneCopoeia=SL504).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) GeneCopoeia; SL504
Encyclopedic resources Wikidata; Q123030369
Entry history
Entry creation05-Oct-2023
Last entry update30-Jan-2024
Version number2