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Cellosaurus HA1 (CVCL_C9AK)

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Cell line name HA1
Synonyms HA-1
Accession CVCL_C9AK
Resource Identification Initiative To cite this cell line use: HA1 (RRID:CVCL_C9AK)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_VU89 (HA1E)CVCL_C9AL (HEK-HT)
Sex of cell Sex unspecified
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=1845837; DOI=10.1016/0042-6822(91)90008-y
Nancy Stewart, Silvia Bacchetti;
Expression of SV40 large T antigen, but not small T antigen, is required for the induction of chromosomal aberrations in transformed human cells.
Virology 180:49-57(1991)

PubMed=9843956; DOI=10.1073/pnas.95.25.14723; PMCID=PMC24516
Christopher M. Counter, William Chun Hahn, Wen-Yi Wei, Stephanie Dickinson Caddle, Roderick L. Beijersbergen, Peter Michael Lansdorp, John Michael Sedivy, Robert Allan Weinberg;
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization.
Proc. Natl. Acad. Sci. U.S.A. 95:14723-14728(1998)

PubMed=10440377; DOI=10.1038/22780
William Chun Hahn, Christopher M. Counter, Ante Sven Lundberg, Roderick L. Beijersbergen, Mary W. Brooks, Robert Allan Weinberg;
Creation of human tumour cells with defined genetic elements.
Nature 400:464-468(1999)

Cross-references
Encyclopedic resources Wikidata; Q123031392
Entry history
Entry creation05-Oct-2023
Last entry update14-Aug-2025
Version number5