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Cellosaurus G477NS-Cas9 (CVCL_C9A2)

[Text version]
Cell line name G477NS-Cas9
Accession CVCL_C9A2
Resource Identification Initiative To cite this cell line use: G477NS-Cas9 (RRID:CVCL_C9A2)
Comments Group: Cancer stem cell line.
Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Omics: Phenotyping; CRISPR screening.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C8ZQ (G477)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=30995489; DOI=10.1016/j.celrep.2019.03.047
Graham MacLeod, Danielle Anne Bozek, Nishani Rajakulendran, Vernon Monteiro, Moloud Ahmadi, Zachary Steinhart, Michelle M. Kushida, Helen Yu, Fiona J. Coutinho, Florence M.G. Cavalli, Ian J. Restall ...Show all 17 authors... , Xiao-Guang Hao, Traver Hart, Hema Artee Luchman, Samuel Weiss, Peter Benjamin Dirks, Stephane Angers; Show fewer authors
Genome-wide CRISPR-Cas9 screens expose genetic vulnerabilities and mechanisms of temozolomide sensitivity in glioblastoma stem cells.
Cell Rep. 27:971-986.e9(2019)

Cross-references
CRISP screens repositories BioGRID_ORCS_Cell_line; 1074
Encyclopedic resources Wikidata; Q123031333
Entry history
Entry creation05-Oct-2023
Last entry update14-Aug-2025
Version number6