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Cellosaurus HF7450-Cas9 (CVCL_C8ZX)

[Text version]
Cell line name HF7450-Cas9
Accession CVCL_C8ZX
Resource Identification Initiative To cite this cell line use: HF7450-Cas9 (RRID:CVCL_C8ZX)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; B.cereus Bsr.
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Omics: Phenotyping; CRISPR screening.
Cell type: Neural stem cell; CL=CL_0000047.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C8ZU (HF7450)
Age at sampling Fetus
Category Somatic stem cell
Publications

PubMed=30995489; DOI=10.1016/j.celrep.2019.03.047
MacLeod G., Bozek D.A., Rajakulendran N., Monteiro V., Ahmadi M., Steinhart Z., Kushida M.M., Yu H., Coutinho F.J., Cavalli F.M.G., Restall I.J., Hao X.-G., Hart T., Luchman H.A., Weiss S., Dirks P.B., Angers S.
Genome-wide CRISPR-Cas9 screens expose genetic vulnerabilities and mechanisms of temozolomide sensitivity in glioblastoma stem cells.
Cell Rep. 27:971-986.e9(2019)

Cross-references
CRISP screens repositories BioGRID_ORCS_Cell_line; 1066
Encyclopedic resources Wikidata; Q123031670
Entry history
Entry creation05-Oct-2023
Last entry update10-Apr-2025
Version number5