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Cellosaurus HF6562-Cas9 (CVCL_C8ZW)

[Text version]
Cell line name HF6562-Cas9
Accession CVCL_C8ZW
Resource Identification Initiative To cite this cell line use: HF6562-Cas9 (RRID:CVCL_C8ZW)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P33967; Bacillus cereus Bsr.
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Omics: Phenotyping; CRISPR screening.
Cell type: Neural stem cell; CL=CL_0000047.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C8ZT (HF6562)
Age at sampling Fetus
Category Somatic stem cell
Publications

PubMed=30995489; DOI=10.1016/j.celrep.2019.03.047
Graham MacLeod, Danielle Anne Bozek, Nishani Rajakulendran, Vernon Monteiro, Moloud Ahmadi, Zachary Steinhart, Michelle M. Kushida, Helen Yu, Fiona J. Coutinho, Florence M.G. Cavalli, Ian J. Restall ...Show all 17 authors... , Xiao-Guang Hao, Traver Hart, Hema Artee Luchman, Samuel Weiss, Peter Benjamin Dirks, Stephane Angers; Show fewer authors
Genome-wide CRISPR-Cas9 screens expose genetic vulnerabilities and mechanisms of temozolomide sensitivity in glioblastoma stem cells.
Cell Rep. 27:971-986.e9(2019)

Cross-references
CRISP screens repositories BioGRID_ORCS_Cell_line; 1065
Encyclopedic resources Wikidata; Q123031668
Entry history
Entry creation05-Oct-2023
Last entry update14-Aug-2025
Version number6