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Cellosaurus 68-41-Cas9 (CVCL_C8ZA)

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Cell line name 68-41-Cas9
Accession CVCL_C8ZA
Resource Identification Initiative To cite this cell line use: 68-41-Cas9 (RRID:CVCL_C8ZA)
Comments Characteristics: T-cell hybridoma.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Omics: Phenotyping; CRISPR screening.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_C8Z9 (68-41)
Category Hybridoma
Publications

PubMed=28768188; DOI=10.1016/j.celrep.2017.07.027
Masahiro Okada, Shunsuke Chikuma, Taisuke Kondo, Sana Hibino, Hiroaki Machiyama, Tadashi Yokosuka, Miyako Nakano, Akihiko Yoshimura;
Blockage of core fucosylation reduces cell-surface expression of PD-1 and promotes anti-tumor immune responses of T cells.
Cell Rep. 20:1017-1028(2017)

Cross-references
CRISP screens repositories BioGRID_ORCS_Cell_line; 1207
Encyclopedic resources Wikidata; Q123030311
Entry history
Entry creation05-Oct-2023
Last entry update14-Aug-2025
Version number5