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Cellosaurus PER-403 (CVCL_C8YK)

[Text version]
Cell line name PER-403
Synonyms Per403
Accession CVCL_C8YK
Resource Identification Initiative To cite this cell line use: PER-403 (RRID:CVCL_C8YK)
Comments Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Thoracic cavity; UBERON=UBERON_0002224.
Sequence variations
Disease NUT carcinoma (NCIt: C45716)
NUT midline carcinoma (ORDO: Orphanet_443167)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 11Y
Category Cancer cell line
Publications

PubMed=1785673; DOI=10.1097/00043426-199124000-00011
Ursula R. Kees, Marie T. Mulcahy, Michael Lawrence Nesbit Willoughby;
Intrathoracic carcinoma in an 11-year-old girl showing a translocation t(15;19).
Am. J. Pediatr. Hematol. Oncol. 13:459-464(1991)

PubMed=17934517; DOI=10.1038/sj.onc.1210852
Christopher Alexander French, Cherie L. Ramirez, Julia Kolmakova, Tyler T. Hickman, Michael J. Cameron, M.E. Thyne, Jeffery L. Kutok, Jeffrey A. Toretsky, A.K. Tadavarthy, Ursula R. Kees, Jonathan A. Fletcher, Jon Christopher Aster;
BRD-NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells.
Oncogene 27:2237-2242(2008)

PubMed=21447744; DOI=10.1158/0008-5472.CAN-10-3513; PMCID=PMC3070805
Brian E. Schwartz, Matthias D. Hofer, Madeleine E. Lemieux, Daniel Evan Bauer, Michael J. Cameron, Nathan H. West, Elin S. Agoston, Nicolas Reynoird, Saadi Khochbin, Tan A. Ince, Amanda L. Christie ...Show all 19 authors... , Katherine A. Janeway, Sara Oakes Vargas, Antonio Rafael Perez-Atayde, Jon Christopher Aster, Stephen Earl Sallan, Andrew L. Kung, James E. Bradner, Christopher Alexander French; Show fewer authors
Differentiation of NUT midline carcinoma by epigenomic reprogramming.
Cancer Res. 71:2686-2696(2011)

PubMed=23128391; DOI=10.1038/onc.2012.487
Katherine Thompson-Wicking, Richard W. Francis, Anja Stirnweiss, Emanuela Ferrari, Mat D. Welch, Elizabeth G. Baker, Ashleigh R. Murch, Alexander M. Gout, Kim Warwick Carter, Adrian K. Charles, Marianne B. Phillips ...Show all 13 authors... , Ursula R. Kees, Alex H. Beesley; Show fewer authors
Novel BRD4-NUT fusion isoforms increase the pathogenic complexity in NUT midline carcinoma.
Oncogene 32:4664-4674(2013)

PubMed=24518598; DOI=10.1038/bjc.2014.54; PMCID=PMC3950881
Alex H. Beesley, Anja Stirnweiss, Emanuela Ferrari, Raelene Endersby, Meegan Howlett, Timothy W. Failes, Greg M. Arndt, Adrian K. Charles, Catherine Helen Cole, Ursula R. Kees;
Comparative drug screening in NUT midline carcinoma.
Br. J. Cancer 110:1189-1198(2014)

PubMed=29348827; DOI=10.18632/oncotarget.22862; PMCID=PMC5762512
Anja Stirnweiss, Joyce Oommen, Rishi S. Kotecha, Ursula R. Kees, Alex H. Beesley;
Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma-an aggressive and fatal disease.
Oncotarget 8:112313-112329(2017)

Cross-references
Encyclopedic resources Wikidata; Q123033260
Entry history
Entry creation05-Oct-2023
Last entry update10-Apr-2025
Version number4