Cellosaurus logo
expasy logo

Cellosaurus (CVCL_C8Y1)

[Text][XML][JSON]
Comments Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK2010-071.
Population: Caucasian.
Omics: Proteomics; Expression; Reverse-phase protein array.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Uterus; UBERON=UBERON_0000995.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1096Ter (c.3286C>T); ClinVar=VCV000156475; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Leufs*9 (c.4666delA); ClinVar=VCV000156477; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Arg88Gln (c.263G>A); ClinVar=VCV000376049; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Thr319fs*1 (c.955_958delACTT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Asn323fs*2 (c.968_969insA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Val654Cysfs*4 (c.1959delA); ClinVar=VCV002724056; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (from parent cell line).
Disease Uterine corpus leiomyosarcoma (NCIt: C6340)
Leiomyosarcoma of the corpus uteri (ORDO: Orphanet_213625)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0533 (SK-UT-1)
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): ATCC=HTB-115; CLS=300406; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,11
D2S133819,21
D3S135815,16
D5S81810,11
D7S8209,10
D8S117914,15
D13S31710,13
D16S53912,14
D18S5111,17
D19S43312,13
D21S1129,32.2
FGA22,23
Penta D11,14
Penta E17
TH017
TPOX5,8 (PubMed=25877200)
8 (ATCC=HTB-115; CLS=300406)
vWA16

Run an STR similarity search on this cell line
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number33