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Cellosaurus MDA-MB-468-Luc (CVCL_C8XW)

[Text version]
Cell line name MDA-MB-468-Luc
Accession CVCL_C8XW
Resource Identification Initiative To cite this cell line use: MDA-MB-468-Luc (RRID:CVCL_C8XW)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Population: African American.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; 9588; PTEN; Simple; c.253+1G>T; ClinVar=VCV000189475; Zygosity=Homozygous; Note=Splice donor mutation (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Simple; c.265_2787del2523; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0419 (MDA-MB-468)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Ubigene; YC-D009-Luc-P
Encyclopedic resources Wikidata; Q123033028
Entry history
Entry creation05-Oct-2023
Last entry update30-Jan-2024
Version number2