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Cellosaurus CAOV3 (R) (CVCL_C8XN)

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Cell line name CAOV3 (R)
Accession CVCL_C8XN
Resource Identification Initiative To cite this cell line use: CAOV3 (R) (RRID:CVCL_C8XN)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_45863; Paclitaxel (Taxol).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136Ter (c.406C>T); ClinVar=VCV001802458; Zygosity=Homozygous (from parent cell line).
Disease High grade ovarian serous adenocarcinoma (NCIt: C105555)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0201 (Caov-3)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=33519462; DOI=10.3389/fphar.2020.600994; PMCID=PMC7838559
Ya-Qing Zhang, Hong-Yun Gan, Fei Zhao, Xiao-Mei Ma, Xiao-Feng Xie, Rui Huang, Jin Zhao;
CPEB4-promoted paclitaxel resistance in ovarian cancer in vitro relies on translational regulation of CSAG2.
Front. Pharmacol. 11:600994.1-600994.10(2020)

Cross-references
Encyclopedic resources Wikidata; Q123030855
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number3