Cellosaurus logo
expasy logo

Cellosaurus U2OS EZHIP KO (CVCL_C8V6)

[Text][XML][JSON]
Cell line name U2OS EZHIP KO
Synonyms C67-KO U2OS
Accession CVCL_C8V6
Resource Identification Initiative To cite this cell line use: U2OS EZHIP KO (RRID:CVCL_C8V6)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:33738; EZHIP.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=33186520; DOI=10.1016/j.ccell.2020.10.009; PMCID=PMC8455074
Ji-Chang Han, Meng Yu, Yi-Qin Bai, Jian-Zhong Yu, Fei Jin, Chen Li, Rong Zeng, Jing-Hong Peng, Ao Li, Xiao-Min Song, Hao Li ...Show all 13 authors... , Dian-Qing Wu, Lin Li; Show fewer authors
Elevated CXorf67 expression in PFA ependymomas suppresses DNA repair and sensitizes to PARP inhibitors.
Cancer Cell 38:844-856.e7(2020)

Cross-references
Encyclopedic resources Wikidata; Q123033671
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number3