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Cellosaurus SH-SY5Y DNAJC5 KD (CVCL_C8UQ)

[Text version]
Cell line name SH-SY5Y DNAJC5 KD
Synonyms SH-SY5Y-DNAJC5-KD
Accession CVCL_C8UQ
Resource Identification Initiative To cite this cell line use: SH-SY5Y DNAJC5 KD (RRID:CVCL_C8UQ)
Comments Population: Caucasian.
Knockout cell: Method=shRNA knockdown; HGNC; HGNC:16235; DNAJC5.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0019 (SH-SY5Y)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
Publications

PubMed=36626307; DOI=10.7554/eLife.85837; PMCID=PMC9876576
Shen-Jie Wu, Nancy C. Hernandez Villegas, Daniel W. Sirkis, Iona Thomas-Wright, Richard Wade-Martins, Randy Wayne Schekman;
Unconventional secretion of alpha-synuclein mediated by palmitoylated DNAJC5 oligomers.
eLife 12:e85837.1-e85837.29(2023)

Cross-references
Encyclopedic resources Wikidata; Q123033477
Entry history
Entry creation05-Oct-2023
Last entry update19-Dec-2024
Version number3