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Cellosaurus HeLa HaloTag-LC3 (CVCL_C8QC)

[Text version]
Cell line name HeLa HaloTag-LC3
Accession CVCL_C8QC
Resource Identification Initiative To cite this cell line use: HeLa HaloTag-LC3 (RRID:CVCL_C8QC)
Comments Population: African American.
Characteristics: Stably expresses HaloTag-LC3 to measure autophagic flux.
Knockout cell: Method=CRISPR/Cas9; HGNC; 20962; ATG3.
Transfected with: RGD; 621315; Map1lc3b.
Transfected with: UniProtKB; P0A3G2; Rhodococcus rhodochrous dhaA (mutated = Halo-Tag).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C7IT (HeLa S3 ATG3 KO)
CVCL_C8QE (HeLa HaloTag-LC3/ATG3-C264A-mCherry)CVCL_C8QI (HeLa HaloTag-LC3/ATG3-H262A-mCherry)CVCL_C8QK (HeLa HaloTag-LC3/ATG3-H266A-mCherry)
CVCL_C8QL (HeLa HaloTag-LC3/ATG3-K208D-mCherry)CVCL_C8QM (HeLa HaloTag-LC3/ATG3-K62D/K64D-mCherry)CVCL_C8QD (HeLa HaloTag-LC3/ATG3-mCherry)
CVCL_C8QJ (HeLa HaloTag-LC3/ATG3-R265A-mCherry)CVCL_C8QH (HeLa HaloTag-LC3/ATG3-T244A-mCherry)CVCL_C8QF (HeLa HaloTag-LC3/ATG3-Y209A-mCherry)
CVCL_C8QG (HeLa HaloTag-LC3/ATG3-Y210A-mCherry)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

Rao S.-L., Strong L.M., Ren X.-F., Skulsuppaisarn M., Lazarou M., Hurley J.H., Hummer G.
Three-step docking by WIPI2, ATG16L1 and ATG3 delivers LC3 to the phagophore.
bioRxiv 2023:07.17.549391-07.17.549391(2023)

Encyclopedic resources Wikidata; Q123031606
Entry history
Entry creation05-Oct-2023
Last entry update30-Jan-2024
Version number2