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Cellosaurus Mvt1 (CVCL_C8Q2)

[Text version]
Cell line name Mvt1
Synonyms MVT1; Mvt-1; MVT-1
Accession CVCL_C8Q2
Resource Identification Initiative To cite this cell line use: Mvt1 (RRID:CVCL_C8Q2)
Comments Characteristics: Contains two distinct populations; CD24- cells (64.1%) and CD24+ cells (35.9%) (PubMed=26484297).
Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:97250; Myc.
Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:103178; Vegfa.
Transformant: MMTV/c-Myc.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: FVB MMTV-c-myc/vegf double transgenic.
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=15180438; DOI=10.1290/1543-706X(2004)40<14:ECOPMT>2.0.CO;2
Pei X.-F., Noble M.S., Davoli M.A., Rosfjord E., Tilli M.T., Furth P.A., Russell R., Johnson M.D., Dickson R.B.
Explant-cell culture of primary mammary tumors from MMTV-c-Myc transgenic mice.
In Vitro Cell. Dev. Biol. Anim. 40:14-21(2004)

PubMed=26040280; DOI=10.1186/s13058-015-0589-9; PMCID=PMC4479226
Rostoker R., Abelson S., Genkin I., Ben-Shmuel S., Sachidanandam R., Scheinman E.J., Bitton-Worms K., Shen-Orr Z., Caspi A., Tzukerman M., LeRoith D.
CD24(+) cells fuel rapid tumor growth and display high metastatic capacity.
Breast Cancer Res. 17:78.1-78.14(2015)

PubMed=26484297; DOI=10.1016/j.gdata.2015.06.032; PMCID=PMC4583690
Rostoker R., Jayaprakash A.D., Sachidanandam R., LeRoith D.
Deep sequencing of mRNA in CD24(-) and CD24(+) mammary carcinoma Mvt1 cell line.
Genom. Data 5:399-401(2015)

Cross-references
Anatomy/cell type resources BTO; BTO_0006554
Encyclopedic resources Wikidata; Q123033138
Gene expression databases GEO; GSE68746
Entry history
Entry creation05-Oct-2023
Last entry update10-Apr-2025
Version number4