Cellosaurus BCLC-5-C8.1 (CVCL_C8JL)
| Cell line name | BCLC-5-C8.1 | |
|---|---|---|
| Accession | CVCL_C8JL | |
| Resource Identification Initiative | To cite this cell line use: BCLC-5-C8.1 (RRID:CVCL_C8JL) | |
| Comments | Characteristics: Transfected with a construct containing a neomycin resistance selectable marker (SGR-JFH1-neo) and cured of HCV RNA by interferon-alpha treatment (PubMed=28751105). Virology: More permissive for hepatitis C virus (HCV) RNA replication than the parental cells (PubMed=28751105). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Derived from site: In situ; Liver; UBERON=UBERON_0002107. Cell type: Epithelial cell; CL=CL_0000066. | |
| Disease | Hepatitis C infection (NCIt: C3098) Adult hepatocellular carcinoma (NCIt: C7956) Cirrhosis (NCIt: C2951) Adult hepatocellular carcinoma (ORDO: Orphanet_210159) | |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | |
| Hierarchy | Parent: CVCL_LC50 (BCLC-5) Children:
| |
| Sex of cell | Female | |
| Age at sampling | 48Y | |
| Category | Cancer cell line | |
| Publications | PubMed=28751105; DOI=10.1016/j.virusres.2017.07.018 | |
| Cross-references | ||
| Encyclopedic resources | Wikidata; Q123030775 | |
| Entry history | ||
| Entry creation | 05-Oct-2023 | |
| Last entry update | 14-Aug-2025 | |
| Version number | 4 | |