Cellosaurus cell line (CVCL

Entry history
Comments	Group: Patented cell line. Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12445. Characteristics: Expresses the variable light and heavy chains of the mAB 6G4.2.5 produced by the hybridoma of the same name (Cellosaurus=CVCL_J003). Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE). Transformant: NCIt; C44386; Gamma radiation. Derived from site: In situ; Ovary; UBERON=UBERON_0000992. Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations	Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line). Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy	Parent: CVCL_8844 (CHO DP-12)
Sex of cell	Female
Age at sampling	Adult
Category	Transformed cell line
Entry creation	06-Jun-2012
Last entry update	19-Dec-2024
Version number	12