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Cellosaurus RAW-Kb-Mito gB30-694 Xbp1 KO (CVCL_C8HF)

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Cell line name RAW-Kb-Mito gB30-694 Xbp1 KO
Synonyms RAW 264.7 Xbp1 KO; XBP1 KO RAW 264.7
Accession CVCL_C8HF
Resource Identification Initiative To cite this cell line use: RAW-Kb-Mito gB30-694 Xbp1 KO (RRID:CVCL_C8HF)
Comments Characteristics: Transfected with a pIRES-gB30-694-Mito vector that contains the mitochondrial matrix-targeting sequence from human COX8A followed by HSV-1 gB30-694 (from parent cell line).
Knockout cell: Method=CRISPR/Cas9; MGI; MGI:98970; Xbp1.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:2294; COX8A (Note=With p.Pro30_Glu69del).
Genetic integration: Method=Transfection; Gene=MGI; MGI:95904; H2-K1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr.
Genetic integration: Method=Transfection; Gene=UniProtKB; P06436; Human herpesvirus 1 glycoprotein B (gB) (Note=With p.Met1_Ala29del and p.Asp695_Leu903del = gB30-694).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 11788; Abelson mouse leukemia virus (AbMuLV).
Miscellaneous: Cell line information from personal communication of Rodriguez-Moya, Lilia.
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: Macrophage; CL=CL_0000235.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_C8HA (RAW-Kb-Mito gB30-694)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Cross-references
Encyclopedic resources Wikidata; Q123033325
Entry history
Entry creation05-Oct-2023
Last entry update10-Apr-2025
Version number4