Cellosaurus logo
expasy logo

Cellosaurus Calu6/Beta2 (CVCL_C8GA)

[Text version]
Cell line name Calu6/Beta2
Accession CVCL_C8GA
Resource Identification Initiative To cite this cell line use: Calu6/Beta2 (RRID:CVCL_C8GA)
Comments Population: Caucasian.
Characteristics: Transfected with a IL12RB2/pEGFP-N1 construct (PubMed=19582164).
Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:5972; IL12RB2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Cell type: Epithelial cell; CL=CL_0000066.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61Lys (c.180_181TC>CA) (c.180_181delinsCA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0236 (Calu-6)
Sex of cell Female
Age at sampling 61Y
Category Cancer cell line
Publications

PubMed=19582164; DOI=10.1371/journal.pone.0006119; PMCID=PMC2702099
Irma Airoldi, Emma Di Carlo, Claudia Cocco, Emanuela Caci, Michele Cilli, Carlo Sorrentino, Gabriella Sozzi, Silvano Ferrini, Sandra Rosini, Giulia Bertolini, Mauro Truini ...Show all 15 authors... , Francesco Grossi, Luis Juan Vicente Galietta, Domenico Ribatti, Vito Pistoia; Show fewer authors
IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions.
PLoS ONE 4:e6119.1-e6119.11(2009)

Cross-references
Encyclopedic resources Wikidata; Q123030851
Entry history
Entry creation05-Oct-2023
Last entry update14-Aug-2025
Version number6