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Cellosaurus OS766 (CVCL_C8FZ)

[Text version]
Cell line name OS766
Accession CVCL_C8FZ
Resource Identification Initiative To cite this cell line use: OS766 (RRID:CVCL_C8FZ)
Comments Characteristics: Established from a patient-derived xenograft established by implantation of the original tumor under the renal capsule of NSG mice (PubMed=37703185).
Omics: Genomics; Whole genome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: Metastatic; Bone, femur; UBERON=UBERON_0000981.
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 30Y
Category Cancer cell line
STR profile Source(s): PubMed=37703185

Markers:
AmelogeninX
CSF1PO10
D5S81813
D7S82011
D13S31712,13
D16S53911,14
TH016,9.3
TPOX11
vWA17

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Publications

PubMed=37703185; DOI=10.1158/1078-0432.CCR-23-0873; PMCID=PMC10870121
Courtney R. Schott, Amanda Lynn Koehne, Leanne C. Sayles, Elizabeth P. Young, Cuyler Luck, Katharine Yu, Alex G. Lee, Marcus R. Breese, Stanley G. Leung, Hang Xu, Avanthi Tayi Shah ...Show all 27 authors... , Heng-Yi Liu, Aviv Spillinger, Inge H. Behroozfard, Kieren D. Marini, Phuong T. Dinh, Maria Victoria Pons-Ventura, Emma N. Vanderboon, Florette K. Hazard, Soo-Jin Cho, Raffi S. Avedian, David G. Mohler, Melissa Zimel, Rosanna Wustrack, Christina Curtis, Marina Sirota, Eric Alejandro Sweet-Cordero; Show fewer authors
Osteosarcoma PDX-derived cell line models for preclinical drug evaluation demonstrate metastasis inhibition by dinaciclib through a genome-targeted approach.
Clin. Cancer Res. 30:849-864(2024)

Cross-references
Encyclopedic resources Wikidata; Q123033229
Entry history
Entry creation29-Jun-2023
Last entry update10-Apr-2025
Version number3