Cellosaurus cell line SBOT-4 (CVCL

Cross-references
Cell line name	SBOT-4
Accession	CVCL_C8DL
Resource Identification Initiative	To cite this cell line use: SBOT-4 (RRID:CVCL_C8DL)
Comments	From: Canadian Ovarian Tissue Bank, University of British Columbia; Vancouver; Canada. Senescence: Proliferates rapidly for 2-3 passages (approximately 10-12 PDLs) but then becomes stationary and eventually dies (PubMed=18217967). Omics: Variations; Array-based CGH. Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=18217967).
Disease	Borderline ovarian serous tumor (NCIt: C5226) Malignant epithelial tumor of ovary (ORDO: Orphanet_398934)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	41Y
Category	Finite cell line
Publications	PubMed=18217967; DOI=10.1111/j.1525-1438.2007.01171.x Michelle M.M. Woo, Clara M. Salamanca, Melinda A. Miller, Jaime E. Symowicz, Peter C.K. Leung, Carla Oliveira, Thomas G. Ehlen, Cyril Blake Gilks, David G. Huntsman, Nelly Auersperg; Serous borderline ovarian tumors in long-term culture: phenotypic and genotypic distinction from invasive ovarian carcinomas. Int. J. Gynecol. Cancer 18:1234-1247(2008)
Encyclopedic resources	Wikidata; Q123033399
Entry history
Entry creation	29-Jun-2023
Last entry update	10-Apr-2025
Version number	5