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Cellosaurus SW620 M13KD (CVCL_C8D7)

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Cell line name SW620 M13KD
Synonyms SW620 MUC13 KnockDown
Accession CVCL_C8D7
Resource Identification Initiative To cite this cell line use: SW620 M13KD (RRID:CVCL_C8D7)
Comments Population: Caucasian.
Doubling time: 20.5 hours (PubMed=24097071).
Knockout cell: Method=shRNA knockdown; HGNC; HGNC:7511; MUC13.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0547 (SW620)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Publications

PubMed=24097071; DOI=10.1007/s00535-013-0885-z; PMCID=PMC3979492
Brij K. Gupta, Diane M. Maher, Mara C. Ebeling, Phillip D. Stephenson, Susan E. Puumala, Michael R. Koch, Hiroyuki Aburatani, Meena Jaggi, Subhash C. Chauhan;
Functions and regulation of MUC13 mucin in colon cancer cells.
J. Gastroenterol. 49:1378-1391(2014)

Cross-references
Encyclopedic resources Wikidata; Q123033582
Entry history
Entry creation29-Jun-2023
Last entry update14-Aug-2025
Version number5