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Cellosaurus SCaBER/R (CVCL_C8D5)

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Cell line name SCaBER/R
Accession CVCL_C8D5
Resource Identification Initiative To cite this cell line use: SCaBER/R (RRID:CVCL_C8D5)
Comments Population: African American.
Selected for resistance to: ChEBI; CHEBI_195316; N-7-(2-(nitrophenyldithio)ethyl)mitomycin C (BMY-25067).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Leu (c.329G>T); ClinVar=VCV000406597; Zygosity=Homozygous (from parent cell line).
Disease Bladder squamous cell carcinoma (NCIt: C4031)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3599 (SCaBER)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=7656243; DOI=10.1016/0304-3835(95)03864-s
Shivendra V. Singh, Bing H. Xu, Vicram Gupta, Erling O. Emerson, Howard Allen Zaren, Jitesh P. Jani;
Characterization of a human bladder cancer cell line selected for resistance to BMY 25067, a novel analogue of mitomycin C.
Cancer Lett. 95:49-56(1995)

Cross-references
Encyclopedic resources Wikidata; Q123033401
Entry history
Entry creation29-Jun-2023
Last entry update19-Dec-2024
Version number4