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Cellosaurus PaCa 5061 (CVCL_C886)

[Text version]
Cell line name PaCa 5061
Synonyms PaCa-5061; PaCa5061
Accession CVCL_C886
Resource Identification Initiative To cite this cell line use: PaCa 5061 (RRID:CVCL_C886)
Comments Doubling time: 30-48 hours (PubMed=20553613).
Omics: Transcriptomics; Microarray.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=20553613; DOI=10.1186/1471-2407-10-295; PMCID=PMC2927995
Tatyana Kalinina, Cenap Gungor, Sabrina Thieltges, Maren Moller-Krull, Eva-Maria Murga Penas, Daniel Wicklein, Thomas Streichert, Udo Schumacher, Viacheslav Kalinin, Ronald Simon, Benjamin Otto ...Show all 17 authors... , Judith Dierlamm, Heidi Schwarzenbach, Katharina E. Effenberger, Maximilian Bockhorn, Jakob Robert Izbicki, Emre F. Yekebas; Show fewer authors
Establishment and characterization of a new human pancreatic adenocarcinoma cell line with high metastatic potential to the lung.
BMC Cancer 10:295.1-295.13(2010)

PubMed=21632553; DOI=10.1158/0008-5472.CAN-11-0036
Cenap Gungor, Hilke Zander, Katharina E. Effenberger, Yogesh K. Vashist, Tatyana Kalinina, Jakob Robert Izbicki, Emre F. Yekebas, Maximilian Bockhorn;
Notch signaling activated by replication stress-induced expression of midkine drives epithelial-mesenchymal transition and chemoresistance in pancreatic cancer.
Cancer Res. 71:5009-5019(2011)

DOI=10.4172/2324-9293.1000104
Markus Udo Wagenhauser, Felix Ruckert, Marco Niedergethmann, Robert Grutzmann, Hans-Detlev Saeger;
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)

PubMed=22490524; DOI=10.1136/gutjnl-2011-300629
Florian Gebauer, Daniel Wicklein, Katrin Stubke, Nina Nehmann, Anna Schmidt, Johannes Salamon, Kersten Peldschus, Michael Fabian Nentwich, Gerhard Adam, Genrich V. Tolstonog, Maximilian Bockhorn ...Show all 14 authors... , Jakob Robert Izbicki, Christoph Wagener, Udo Schumacher; Show fewer authors
Selectin binding is essential for peritoneal carcinomatosis in a xenograft model of human pancreatic adenocarcinoma in pfp--/rag2-- mice.
Gut 62:741-750(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C886
Encyclopedic resources Wikidata; Q54937416
Polymorphism and mutation databases Cosmic; 1352405
IARC_TP53; 28456
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number17