Cellosaurus cell line MM396 (CVCL

Cellosaurus MM396 (CVCL_C841)

Cross-references
Cell line name	MM396
Synonyms	MM 396
Accession	CVCL_C841
Resource Identification Initiative	To cite this cell line use: MM396 (RRID:CVCL_C841)
Comments	Omics: Variations; CNV analysis. Omics: Variations; SNP array analysis.
Sequence variations	Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=17363583). Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Pro81Leu (c.242C>T); ClinVar=VCV000833629; Zygosity=Unspecified (PubMed=9354451; PubMed=17363583).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=3756862 Kevin Maynard, Peter G. Parsons; Cross-sensitivity of methylating agents, hydroxyurea, and methotrexate in human tumor cells of the Mer- phenotype. Cancer Res. 46:5009-5013(1986) PubMed=9354451 Marina Castellano, Pamela M. Pollock, Marilyn K. Walters, Louise E. Sparrow, Louise M. Down, Brian G. Gabrielli, Peter G. Parsons, Nicholas K. Hayward; CDKN2A/p16 is inactivated in most melanoma cell lines. Cancer Res. 57:4868-4875(1997) PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152 Mitchell S. Stark, Nicholas K. Hayward; Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays. Cancer Res. 67:2632-2642(2007)
Cell line databases/resources	cancercelllines; CVCL_C841
Encyclopedic resources	Wikidata; Q54906120
Gene expression databases	GEO; GSM226661
Polymorphism and mutation databases	Cosmic; 928727 Progenetix; CVCL_C841
Entry history
Entry creation	22-Oct-2012
Last entry update	10-Apr-2025
Version number	17