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Cellosaurus MM200 (CVCL_C836)

[Text version]
Cell line name MM200
Synonyms MM 200
Accession CVCL_C836
Resource Identification Initiative To cite this cell line use: MM200 (RRID:CVCL_C836)
Comments Omics: Transcriptomics; Microarray.
Omics: Variations; CNV analysis.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Sequence variations
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line
Publications

PubMed=830403
Patricia D. Goss, Peter G. Parsons;
The effect of hyperthermia and melphalan on survival of human fibroblast strains and melanoma cell lines.
Cancer Res. 37:152-156(1977)

PubMed=294576; DOI=10.3109/00313027909059039
Pauline D. Muir, Friedrich Walter Gunz;
A cytogenetic study of eight human melanoma cell lines.
Pathology 11:597-606(1979)

PubMed=460945; DOI=10.3109/00313027909061945
John Hebden Pope, Leanne E. Morrison, Denis J. Moss, Peter G. Parsons, Regis Mary Dunne;
Human malignant melanoma cell lines.
Pathology 11:191-195(1979)

PubMed=3756862
Kevin Maynard, Peter G. Parsons;
Cross-sensitivity of methylating agents, hydroxyurea, and methotrexate in human tumor cells of the Mer- phenotype.
Cancer Res. 46:5009-5013(1986)

PubMed=1697409
Georgia Chenevix-Trench, Nicholas Gordon Martin, Kay Adrian Oswald Ellem;
Gene expression in melanoma cell lines and cultured melanocytes: correlation between levels of c-src-1, c-myc and p53.
Oncogene 5:1187-1193(1990)

PubMed=7520026; DOI=10.1002/ijc.2910580413
Peter Hersey, Zhao-Yi Si, Melanie J. Smith, Wayne D. Thomas;
Expression of the co-stimulatory molecule B7 on melanoma cells.
Int. J. Cancer 58:527-532(1994)

PubMed=8980186; DOI=10.1002/(SICI)1097-0215(19961211)68:6<795::AID-IJC18>3.0.CO;2-#
Wayne D. Thomas, Melanie J. Smith, Zhao-Yi Si, Peter Hersey;
Expression of the co-stimulatory molecule CD40 on melanoma cells.
Int. J. Cancer 68:795-801(1996)

PubMed=9354451
Marina Castellano, Pamela M. Pollock, Marilyn K. Walters, Louise E. Sparrow, Louise M. Down, Brian G. Gabrielli, Peter G. Parsons, Nicholas K. Hayward;
CDKN2A/p16 is inactivated in most melanoma cell lines.
Cancer Res. 57:4868-4875(1997)

PubMed=9725211; DOI=10.4049/jimmunol.161.5.2195
Wayne D. Thomas, Peter Hersey;
TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis in Fas ligand-resistant melanoma cells and mediates CD4 T cell killing of target cells.
J. Immunol. 161:2195-2200(1998)

PubMed=10070891; DOI=10.1038/sj.bjc.6690147; PMCID=PMC2362648
Shuraila Francisca Zerp, Andrea van Elsas, Lucy T.C. Peltenburg, Peter I. Schrier;
p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis.
Br. J. Cancer 79:921-926(1999)

PubMed=15048078; DOI=10.1038/sj.onc.1207563
Sandra Pavey, Peter Johansson, Leisl Packer, Jennifer Taylor, Mitchell S. Stark, Pamela M. Pollock, Graeme J. Walker, Glen M. Boyle, Ursula Harper, Sarah-Jane Cozzi, Katherine Hansen ...Show all 20 authors... , Laura Yudt, Chris Schmidt, Peter Hersey, Kay Adrian Oswald Ellem, Michael G.E. O'Rourke, Peter G. Parsons, Paul S. Meltzer, Markus Ringner, Nicholas K. Hayward; Show fewer authors
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
Oncogene 23:4060-4067(2004)

PubMed=17363583; DOI=10.1158/0008-5472.CAN-06-4152
Mitchell S. Stark, Nicholas K. Hayward;
Genome-wide loss of heterozygosity and copy number analysis in melanoma using high-density single-nucleotide polymorphism arrays.
Cancer Res. 67:2632-2642(2007)

PubMed=17516929; DOI=10.1111/j.1600-0749.2007.00375.x
Peter Johansson, Sandra Pavey, Nicholas K. Hayward;
Confirmation of a BRAF mutation-associated gene expression signature in melanoma.
Pigment Cell Res. 20:216-221(2007)

PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676
Ken Dutton-Regester, Darryl Irwin, Priscilla Hunt, Lauren G. Aoude, Varsha Tembe, Gulietta M. Pupo, Cathy Lanagan, Candace D. Carter, Linda O'Connor, Michael O'Rourke, Richard Anthony Scolyer ...Show all 15 authors... , Graham J. Mann, Christopher W. Schmidt, Adrian Herington, Nicholas K. Hayward; Show fewer authors
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Mol. Cancer Ther. 11:888-897(2012)

PubMed=23039341; DOI=10.1186/1476-4598-11-75; PMCID=PMC3554420
Sara A. Byron, David C. Loch, Candice L. Wellens, Andreas Wortmann, Jia-Yi Wu, John Wang, Kenichi Nomoto, Pamela M. Pollock;
Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status.
Mol. Cancer 11:75.1-75.15(2012)

PubMed=23455323; DOI=10.1038/onc.2013.45
Therese M. Becker, Suzanah C. Boyd, Branka Mijatov, Kavitha Gowrishankar, Stephanie Snoyman, Gulietta M. Pupo, Richard Anthony Scolyer, Graham J. Mann, Richard F. Kefford, Xu-Dong Zhang, Helen Rizos;
Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor.
Oncogene 33:1158-1166(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C836
Anatomy/cell type resources BTO; BTO_0005717
Encyclopedic resources Wikidata; Q54906077
Experimental variables resources EFO; EFO_0022617
Gene expression databases GEO; GSM162935
GEO; GSM219446
Polymorphism and mutation databases Cosmic; 889014
Cosmic; 928753
Progenetix; CVCL_C836
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number25