Cellosaurus cell line T142 (CVCL

Cellosaurus T142 (CVCL_C7W3)

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Cell line name

T142

Accession

CVCL_C7W3

Resource Identification Initiative

To cite this cell line use: T142 (RRID:CVCL_C7W3)

Comments

Doubling time: 34.32 +- 3.46 hours (Note=At 6-11th passages), 14.46 +- 1.06 hours (Note=At 60-62th passages) (PubMed=27723895).
Karyotypic information: Monosomy of chromosome 3 and trisomy of chromosome 8 (PubMed=27723895).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.

Sequence variations

Mutation; HGNC; HGNC:4379; GNA11; Simple; p.Gln209Leu (c.626A>T); ClinVar=VCV000376002; Zygosity=Unspecified (PubMed=27723895).

Disease

Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

54Y

Category

Cancer cell line

STR profile

Source(s): PubMed=27723895

Markers:

Amelogenin	X
D1S1656	14,15
D2S441	15
D2S1338	19
D6S1043	Not_detected
D10S1248	14
D12S391	21
D19S433	Not_detected
D22S1045	16
TH01	7,9.3

Publications

PubMed=27723895; DOI=10.1167/iovs.16-19317
Frederic Mouriaux, Karine Zaniolo, Marjorie-Allison Bergeron, Cindy Weidmann, Arnaud de la Fouchardiere, Frederic Fournier, Arnaud Droit, Mohib W. Morcos, Solange Landreville, Sylvain L. Guerin;
Effects of long-term serial passaging on the characteristics and properties of cell lines derived from uveal melanoma primary tumors.
Invest. Ophthalmol. Vis. Sci. 57:5288-5301(2016)

Cross-references

Encyclopedic resources

Wikidata; Q123033597

Gene expression databases

GEO; GSM1499916
GEO; GSM1499917
GEO; GSM1499918

Entry history

Entry creation

29-Jun-2023

Last entry update

10-Apr-2025

Version number