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Cellosaurus HME50-8R (CVCL_C7T3)

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Cell line name HME50-8R
Accession CVCL_C7T3
Resource Identification Initiative To cite this cell line use: HME50-8R (RRID:CVCL_C7T3)
Comments Characteristics: Treated with resveratrol (PubMed=17968319).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met133Thr (c.398T>C); ClinVar=VCV000012357; Zygosity=Heterozygous (from parent cell line).
Disease Li-Fraumeni syndrome (NCIt: C3476)
Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C7SX (HME50-8)
Sex of cell Female
Age at sampling 31Y
Category Spontaneously immortalized cell line
Publications

PubMed=17968319; DOI=10.1038/sj.onc.1210886; PMCID=PMC3397201
Virginia P. Pearce, Jason Sherrell, Zhen-Jun Lou, Levy Kopelovich, Woodring Erik Wright, Jerry W. Shay;
Immortalization of epithelial progenitor cells mediated by resveratrol.
Oncogene 27:2365-2374(2008)

Cross-references
Encyclopedic resources Wikidata; Q117704491
Entry history
Entry creation21-Mar-2023
Last entry update19-Dec-2024
Version number5