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Cellosaurus HME50 (CVCL_C7T1)

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Cell line name HME50
Accession CVCL_C7T1
Resource Identification Initiative To cite this cell line use: HME50 (RRID:CVCL_C7T1)
Comments Omics: Transcriptomics; Serial analysis of gene expression (SAGE).
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Sequence variations
Disease Li-Fraumeni syndrome (NCIt: C3476)
Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C7ST (HME50-3)CVCL_C7SU (HME50-5)CVCL_C7SV (HME50-6)
CVCL_C7SW (HME50-7)CVCL_C7SX (HME50-8)CVCL_C7SY (HME50-9)
Originate from same individual CVCL_C7T2 ! HMS50
Sex of cell Female
Age at sampling 31Y
Category Finite cell line
Publications

PubMed=7799951; DOI=10.1128/mcb.15.1.425; PMCID=PMC231985
Jerry W. Shay, Gail E. Tomlinson, Mieczyslaw A. Piatyszek, Lauren S. Gollahon;
Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndrome.
Mol. Cell. Biol. 15:425-432(1995)

PubMed=17968319; DOI=10.1038/sj.onc.1210886; PMCID=PMC3397201
Virginia P. Pearce, Jason Sherrell, Zhen-Jun Lou, Levy Kopelovich, Woodring Erik Wright, Jerry W. Shay;
Immortalization of epithelial progenitor cells mediated by resveratrol.
Oncogene 27:2365-2374(2008)

Cross-references
Encyclopedic resources Wikidata; Q117704485
Gene expression databases GEO; GSM383844
GEO; GSM384086
Entry history
Entry creation21-Mar-2023
Last entry update10-Apr-2025
Version number6