| Cell line name |
II-45 |
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| Synonyms |
II45; 45 |
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| Accession |
CVCL_C7RZ |
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| Resource Identification Initiative |
To cite this cell line use: II-45 (RRID:CVCL_C7RZ) |
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| Comments |
Doubling time: 18.5 hours (PubMed=2827488).
Transformant: ChEBI; CHEBI_46666; Crocidolite asbestos.
Misspelling: II-15; PubMed=1309438; Note=In material and methods.
Derived from site: In situ; Peritoneum; UBERON=UBERON_0002358. |
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| Disease |
Rat malignant mesothelioma (NCIt: C60453) |
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| Species of origin |
Rattus norvegicus (Rat)
(NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215. |
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| Sex of cell |
Female |
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| Category |
Cancer cell line |
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| Publications | PubMed=2827488; PMCID=PMC1899808
Craighead J.E., Akley N.J., Gould L.B., Libbus B.L.
Characteristics of tumors and tumor cells cultured from experimental asbestos-induced mesotheliomas in rats.
Am. J. Pathol. 129:448-462(1987) PubMed=1309438
Walker C.L., Bermudez E., Stewart W., Bonner J.C., Molloy C.J., Everitt J.I.
Characterization of platelet-derived growth factor and platelet-derived growth factor receptor expression in asbestos-induced rat mesothelioma.
Cancer Res. 52:301-306(1992) PubMed=8205524
Walker C.L., Rutten A.A.J.J.L., Yuan X.-Q., Pass H.I., Mew D.M., Everitt J.I.
Wilms' tumor suppressor gene expression in rat and human mesothelioma.
Cancer Res. 54:3101-3106(1994) PubMed=7627973
Rutten A.A.J.J.L., Bermudez E., Stewart W., Everitt J.I., Walker C.L.
Expression of insulin-like growth factor II in spontaneously immortalized rat mesothelial and spontaneous mesothelioma cells: a potential autocrine role of insulin-like growth factor II.
Cancer Res. 55:3634-3639(1995) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q117704525
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| Entry history |
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| Entry creation | 21-Mar-2023 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 5 |
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