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Cellosaurus MKN1 CHRNB2 KO-2 (CVCL_C7NJ)

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Cell line name MKN1 CHRNB2 KO-2
Accession CVCL_C7NJ
Resource Identification Initiative To cite this cell line use: MKN1 CHRNB2 KO-2 (RRID:CVCL_C7NJ)
Comments Population: Japanese.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:1962; CHRNB2.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Disease Gastric adenosquamous carcinoma (NCIt: C5474)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1415 (MKN1)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=34331011; DOI=10.1038/s41388-021-01945-9
Mitsuro Kanda, Dai Shimizu, Shunsuke Nakamura, Koichi Sawaki, Shinichi Umeda, Takashi Miwa, Haruyoshi Tanaka, Yoshikuni Inokawa, Norifumi Hattori, Masamichi Hayashi, Chie Tanaka ...Show all 15 authors... , Goro Nakayama, Yohei Iguchi, Masahisa Katsuno, Yasuhiro Kodera; Show fewer authors
Blockade of CHRNB2 signaling with a therapeutic monoclonal antibody attenuates the aggressiveness of gastric cancer cells.
Oncogene 40:5495-5504(2021)

Cross-references
Encyclopedic resources Wikidata; Q117704708
Entry history
Entry creation21-Mar-2023
Last entry update19-Dec-2024
Version number4