Cellosaurus cell line RT112 CP2.5 (CVCL

Cellosaurus RT112 CP2.5 (CVCL_C7JW)

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Cell line name

RT112 CP2.5

Synonyms

CP2.5

Accession

CVCL_C7JW

Resource Identification Initiative

To cite this cell line use: RT112 CP2.5 (RRID:CVCL_C7JW)

Comments

Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.

Sequence variations

Gene fusion; HGNC; HGNC:3690; FGFR3 + HGNC; HGNC:11524; TACC3; Name(s)=FGFR3-TACC3 (from parent cell line).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser183Ter (c.548C>G); ClinVar=VCV000634701; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (from parent cell line).

Disease

Bladder carcinoma (NCIt: C4912)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_C7JV (RT112 CP2)
Children:

CVCL_C7JX (RT112 CP3)

Sex of cell

Female

Age at sampling

Age unspecified