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Cellosaurus HCK1T (CVCL_C7IN)

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Cell line name HCK1T
Synonyms Human Cervical Keratinocytes 1 TERT-immortalized
Accession CVCL_C7IN
Resource Identification Initiative To cite this cell line use: HCK1T (RRID:CVCL_C7IN)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Omics: Proteomics; Subcellular; Secretome; 2DE-MS.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C7IQ (HCK1T-E6)CVCL_C7IR (HCK1T-E6E7)CVCL_C7IS (HCK1T-E7)
Sex of cell Female
Age at sampling Age unspecified
Category Telomerase immortalized cell line
Publications

PubMed=17146442; DOI=10.1038/sj.onc.1210118
Mako Narisawa-Saito, Keisuke Handa, Takashi Yugawa, Shin-ichi Ohno, Masatoshi Fujita, Tohru Kiyono;
HPV16 E6-mediated stabilization of ErbB2 in neoplastic transformation of human cervical keratinocytes.
Oncogene 26:2988-2996(2007)

PubMed=28261610; DOI=10.1155/2017/4180703; PMCID=PMC5316418
Georgia Kontostathi, Jerome Zoidakis, Manousos Makridakis, Vasiliki Lygirou, Georgios Mermelekas, Theofilos Papadopoulos, Konstantinos Vougas, Alexios Vlamis-Gardikas, Peter Drakakis, Dimitrios Loutradis, Antonia Vlahou ...Show all 13 authors... , Nicholas P. Anagnou, Kalliopi I. Pappa; Show fewer authors
Cervical cancer cell line secretome highlights the roles of transforming growth factor-beta-induced protein ig-h3, peroxiredoxin-2, and NRF2 on cervical carcinogenesis.
BioMed Res. Int. 2017:4180703.1-4180703.15(2017)

Cross-references
Encyclopedic resources Wikidata; Q117704475
Entry history
Entry creation21-Mar-2023
Last entry update14-Aug-2025
Version number6