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Cellosaurus BLMRL-HMFG-Mc3 (CVCL_C7HA)

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Cell line name BLMRL-HMFG-Mc3
Synonyms Mc3
Accession CVCL_C7HA
Resource Identification Initiative To cite this cell line use: BLMRL-HMFG-Mc3 (RRID:CVCL_C7HA)
Comments Biotechnology: The monoclonal antibody produced by this hybridoma was used to prepare the humanized Angiolix therapeutic antibody used against breast tumors.
Monoclonal antibody isotype: IgG1.
Monoclonal antibody target: UniProtKB; Q08431; Human MFGE8.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2155 (P3/NS1/1-Ag4.1)
Category Hybridoma
Publications

PubMed=6353626; DOI=10.1007/BF01543043
Roberto L. Ceriani, Jerry A. Peterson, Johnny Y. Lee, Raineldo Moncada, Edward W. Blank;
Characterization of cell surface antigens of human mammary epithelial cells with monoclonal antibodies prepared against human milk fat globule.
Somatic Cell Genet. 9:415-427(1983)

PubMed=2365381; DOI=10.1089/hyb.1990.9.221
Jerry A. Peterson, David T. Zava, Axel K. Duwe, Edward W. Blank, Hector Augusto Battifora, Roberto L. Ceriani;
Biochemical and histological characterization of antigens preferentially expressed on the surface and cytoplasm of breast carcinoma cells identified by monoclonal antibodies against the human milk fat globule.
Hybridoma 9:221-235(1990)

PubMed=7712480
Joseph R. Couto, Edward W. Blank, Jerry A. Peterson, Roberto L. Ceriani;
Anti-BA46 monoclonal antibody Mc3: humanization using a novel positional consensus and in vivo and in vitro characterization.
Cancer Res. 55:1717-1722(1995)

Cross-references
Biological sample resources ABCD; ABCD_AE980
Encyclopedic resources Wikidata; Q117704223
Entry history
Entry creation21-Mar-2023
Last entry update29-Jun-2023
Version number2