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Cellosaurus NS0-hCD20 (CVCL_C6XI)

[Text version]
Cell line name NS0-hCD20
Synonyms NS/0-hCD20; NSO/CD20
Accession CVCL_C6XI
Resource Identification Initiative To cite this cell line use: NS0-hCD20 (RRID:CVCL_C6XI)
Comments Selected for resistance to: ChEBI; CHEBI_63486; 8-azaguanine.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7315; MS4A1.
Cell type: Plasma cell; CL=CL_0000786.
Disease Mouse multiple myeloma (NCIt: C125417)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_3940 (NS0)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

Patent=US8329181
Joel H. Martin, Li-Hsien Wang, Sean Stevens, Erin M. Allison;
Methods for treating B-cell lymphoma by administering an anti-CD20 antibody.
Patent number US8329181, 11-Dec-2012

PubMed=26659273; DOI=10.1038/srep17943; PMCID=PMC4675964
Eric J. Smith, Kara Olson, Lauric J. Haber, Bindu Varghese, Paurene Duramad, Andrew D. Tustian, Adelekan Oyejide, Jessica R. Kirshner, Lauren Canova, Jayanthi Menon, Jennifer Principio ...Show all 18 authors... , Douglas MacDonald, Joel Kantrowitz, Nicholas J. Papadopoulos, Neil Stahl, George D. Yancopoulos, Gavin Thurston, Samuel Davis; Show fewer authors
A novel, native-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeys.
Sci. Rep. 5:17943.1-17943.12(2015)

Cross-references
Encyclopedic resources Wikidata; Q117704733
Entry history
Entry creation21-Mar-2023
Last entry update14-Aug-2025
Version number6