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Cellosaurus 4B12 [Mouse bone] (CVCL_C6WU)

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Cell line name 4B12 [Mouse bone]
Accession CVCL_C6WU
Resource Identification Initiative To cite this cell line use: 4B12 [Mouse bone] (RRID:CVCL_C6WU)
Comments Characteristics: Selected by FACS to be Mac-1+cFms+-RANK1+. Depend on Csf1 for both proliferation and osteoclast differentiation (PubMed=19492422).
Derived from site: In situ; Bone, calvaria; UBERON=UBERON_0004339.
Cell type: Osteoclast; CL=CL_0000092.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: ddY.
Sex of cell Sex unspecified
Age at sampling 14FD
Category Spontaneously immortalized cell line
Publications

PubMed=19492422; DOI=10.1002/jcp.21827; PMCID=PMC4080882
Shigeru Amano, Keisuke Sekine, Lynda Faye Bonewald, Yoshihiro Ohmori;
A novel osteoclast precursor cell line, 4B12, recapitulates the features of primary osteoclast differentiation and function: enhanced transfection efficiency before and after differentiation.
J. Cell. Physiol. 221:40-53(2009)

Cross-references
Encyclopedic resources Wikidata; Q123030286
Entry history
Entry creation21-Mar-2023
Last entry update30-Jan-2024
Version number4